Gilles LAFARGUE, PhD, Maître de Conférences

Université de Lille et Laboratoire PSITEC (EA-4072)


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Neuropsychology, Sense of effort, Will, Agency, Motor intentions, Emotions, Motivation, Efference copy, Schizophrenia, Supplementary motor area, parietal cortex, Cerebral plasticity

Mots clés

Neuropsychologie, Sens de l'effort, Volonté, Agentivité, Intentions motrices, Emotions, Motivation, Copie d'efférence, Schizophrénie, Aire motrice supplémentaire, Cortex pariétal, Plasticité cérébrale


Responsabilités collectives

·       Membre élu du Conseil National des Universités (section 16)

·       Membre élu du Conseil Scientifique de l’Université Charles de Gaulle

·       Responsable des UE « Psychologie Générale et Différentielle » (L1), « Neuroéthique » (L3) et « Neuropsychologie Clinique : de la théorie à la pratique clinique » (L3)


Publications scientifiques

·       Herbet,GMaheu M., Costi E, Lafargue G.Duffau H. (2016). Mapping neuroplastic potential in brain-damaged patients. Brain. 139:829-44.

·       Lemaitre, AL., Luyat, M., Lafargue, G. (2016). Individuals with pronounced schizotypal traits are particularly successful in tickling themselves. Consciousness and Cognition, 41: 64-71.

ü  People With Schizophrenic-Like Traits Are Able To Tickle Themselves

·      Herbet,GLafargue G., Duffau H. (2016). The dorsal cingulate cortex as a critical gateway in the network supporting conscious awareness. Brain. 139: e23. doi: 10.1093/brain/awv381.

·       Herbet, G., Lafargue, G., Almairac, F., Moritz-Gasser, S., Bonnetblanc, F., Duffau, H. (2015). Disrupting the right pars opercularis with electrical stimulation frees the song. Journal of Neurosurgery. In press.

·       Herbet, G., Lafargue, G., Moritz-Gasser, S., de Champfleur, NM., Costi, E., Bonnetblanc, F., Duffau, H. (2015) A Disconnection account of subjective empathy impairments in diffuse low-grade glioma patients. Neuropsychologia, 70, 165-176.

·       Herbet, G., Lafargue, G., Duffau, H. (2015). Rethinking voxel-wise lesion-deficit analysis: A new challenge for computational neuropsychology. Cortex, 64, 413-416.

·       Herbet, G., Lafargue, G., Moritz-Gasser, S., Bonnetblanc, F., Duffau, H. (2015). Interfering with the neural activity of mirror-related frontal areas impairs mentalistic inferences. Brain Structure and Function, 220(4):2159-69.

·       Metral M, Guardia D, Bauwens I, Guerraz M, Lafargue G, Cottencin O, Luyat M. (2014). Painfully thin but locked inside a fatter body: abnormalities in both anticipation and execution of action in anorexia nervosa. BMC Res Notes. 7:707, 1-11.

·       Herbet, G., Lafargue, G., Bonnetblanc F., Moritz-Gasser S., Menjot de Champfleur N., Duffau H. (2014). Inferring a dual-stream model of mentalizing from the disconnection of white matter fibres. Brain, 137:944-59.

·       Herbet, G., Lafargue, G., Moritz-Gasser S., Bonnetblanc F., Duffau H. (2014). Disrupting the connectivity underlying posterior cingulate cortex disconnects consciousness from the external environment. Neuropsychologia, 56:239-244.

·       Herbet, G., Lafargue, G., Bonnetblanc, F., Moritz-Gasser, S., Duffau, H. (2013). Is the right frontal cortex really crucial in the mentalizing network? A longitudinal study in patients with a slow-growing lesion. Cortex. 49(10):2711-27.

·       Lafargue G, Noël M, Luyat. M (2013). In the Elderly, Failure to Update Internal Models Leads to Over-Optimistic Predictions about Upcoming Actions. PLoS ONE 8(1): e51218. doi:10.1371/journal.pone.0051218

·       Guardia, D., Conversy, L, Jardri ,R., Lafargue, G., Thomas, P., et al. (2012). Imagining One’s Own and Someone Else’s Body Actions: Dissociation in Anorexia Nervosa. PLoS ONE 7(8): e43241. doi:10.1371/journal.pone.0043241

·       Jardri, R., Pins, D., Lafargue G., Very, E., Ameller, A., Delmaire, C., Thomas, P. (2011). Increased overlap between the brain areas involved in self-other distinction in schizophrenia. PLoS ONE  9;6(3):e17500.

·       Cléry-Melin M.L., Schmidt, L., Lafargue, G., Baup, N., Fossati, P., Pessiglione, M. (2011). Why don't you try harder? An investigation of effort production in major depression. PLoS ONE.  6(8): e23178. doi:10.1371/journal.pone.0023178

·       Guardia, D., Lafargue, G., Thomas, P., Dodin, V., Cottencin, O., Luyat, M. (2010). Anticipation of body scaled action is modified in anorexia nervosa. Neuropsychologia. 48(13):3961-66.

·       Lafargue, G. (2010). The subjective experience of willed effort in schizophrenia: a neurophenomenological approach. L'Evolution Psychiatrique, 75(3):421-433.

·       Schmidt, L., Palminteri, S., Lafargue, G., Pessiglione, M. (2010). Splitting motivation: unilateral effects of subliminal incentives. Psychological Science, 7: 977-983.

·       Palminteri, S., Boraud, T., Lafargue, G., Dubois, B., Pessiglione, M. (2009). Brain hemispheres selectively track the expected value of contralateral options. Journal of Neuroscience, 29(43):13465-72.

·       Lafargue, G., Franck, N. (2009). Effort awareness and sense of volition in schizophrenia. Consciousness and Cognition, 18, 277-289. pdf-ico

·       Schmidt, L., Cléry-Melin, ML., Lafargue, G., Valabrègue, R., Fossati, P., Dubois, B., Pessiglione, M. (2009). Get aroused and be stronger: emotional facilitation of physical effort in the human brain. Journal of Neuroscience, 29(30), 9450-9457.

·       Lafargue G., Duffau, H. (2008). Awareness of intending to act following parietal cortex resection. Neuropsychologia, 46(11), 2662-2667.

·       Lafargue, G. (2008). Afferent feedback and visual information contribute to the subjective experience of achieved effort. Journal of Applied Physiology,

·       Lafargue, G., Franck, N. (2008). Role of sense of effort in delusions of control. PSN - Psychiatrie, Sciences humaines, Neurosciences, 6, 137–148.

·       Schmidt, L., Forgeot d’Arc, B., Lafargue, G., Galanaud, D., Czernecki, V., Grabli, D., Schüpbach, M., Hartmann, A., Lévy, R., Dubois, B., Pessiglione, M. (2008). Breaking the bridge between money and force: dysfunction of incentive motivation following basal ganglia damage. Brain, 131: 1303-1310.

·       Lafargue, G., D'Amico, A., Thobois, S., Broussolle, E., Sirigu, A. (2008). The ability to assess muscular force in asymmetrical Parkinson's disease. Cortex, 44, 82-89.

·       Lafargue, Gilles., Sirigu, Angela. (2006). The nature of the sense of effort and its neural substratum. Revue Neurologique, 162, 703-712.

·       Lafargue, G. Franck, N., Sirigu, A. (2006). Sense of motor effort in patients with schizophrenia. Cortex, 42, 711-719.

·       Lafargue, G. Paillard, J., Lamarre, Y. Sirigu, A. (2003). Production and perception of grip force without proprioception: is there a sense of effort in deafferented subjects ? European Journal of Neuroscience, 17: 2741-2749.

·       Lafargue G., Sirigu A. (2002). Effort sensation is altered in Huntington's disease. Neuropsychologia, 40(10), 1654-1661.



Vulgarisation scientifique

·       Interview pour l'ACTU - Pourquoi l'aîné est souvent (un peu) plus "intelligent", novembre 2015.

·       Interview pour AtlanticoFatigue de la décision : la raison qui explique pourquoi Mark Zuckerberg porte tous les jours le même t-Shirt, novembre 2014.

·       Interview pour le Parisien – Psycho : Décider, pas si simple ! sept 2014.




  • Schmidt L., Cléry-Melin ML., Lafargue G., Fossati P., Dubois B., Pessiglione M. Why do you try so hard? Dissociating emotional and motivational factors with functional neuroimaging in healthy subjects and behavioral testing in depressed patients. Poster presented at the 9th Annual meeting of the Société des Neurosciences - May 26-29, 2009. Bordeaux, France.
  • Luyat, M., Guardia, D., Lafargue, G., Thomas, P. Does false representation of body in anorexia nervosa affect visual perception of action possibilities? Poster presented at the 9th Annual Meeting of Vision Sciences Society (VSS) May 8-13, 2009. Naples Grande Resort & Club, Naples, Florida

·       Pessiglione, M., Palminteri, S., Schmidt, M., Lafargue, G. (2009). Hemispheric dissociation of the human brain valuation system. 7th Annual Meeting of the Society for neuroeconomics. Neuroeconomics: Decision Making and the Brain. September, 25-27, 2009. Evanston, Illinois.

  • Palminteri, S., Boraud, T., Lafargue, G., Dubois, B., Pessiglione, M. How expected rewards map onto motor effectors: a functional neuroimaging study of action value representation in the human brain. Poster presented at the 38th Annual meeting of the Society for Neuroscience (SfN), Washington, USA, November 15-19, 2008.
  • Delcour M., Lafargue, G. Peut-on amplifier l’effet de l’amorçage subliminal grâce à une suggestion non hypnotique ? Colloque International Francophone du Groupement pour l’étude et les applications médicales de l’hypnose (GEAMH), Paris, France, November 28-29, 2008. Prix Léon Chertok à Marion Delcour.
  • Schmidt, L., Cléry-Melin, ML., Lafargue, G., Fossati, P., Dubois, B., Pessiglione, M. Being aroused makes you stronger: a functional neuroimaging study of effort facilitation by emotional induction. Poster presented at the 38th Annual meeting of the Society for Neuroscience (SfN), Washington, USA, November 15-19, 2008.
  • Lafargue, G., Auclair, D., Thobois, S., Sirigu, A., Broussolle, E. (2004). The ability to grade and to assess muscular force in Parkinson’s disease. 8th Congress of the European Federation of Neurological Societies. Paris, France, September 4-7, 2004. Abstract in European Journal of Neurology, 11 (S2), 107.